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One Blood Draw. More Than 50 Types of Cancer Screened.
Galleri® multi-cancer detection testing is now available to Upper Echelon Medical members. Your own physician orders it, reviews the results with you, and coordinates every next step.
Most Cancers Have No Routine Screening Test
Recommended screening exists for only a few cancers, such as breast, cervical, colorectal, and lung cancer in eligible patients. About half of the cancers diagnosed in the U.S. this year, and most cancer deaths, come from cancer types with no recommended screening test at all.
Cancers like pancreatic, ovarian, esophageal, and liver cancer are often found only after symptoms appear. By then, treatment options are usually fewer. Galleri was built to help close that gap.
What Galleri Is
Galleri is a blood test that looks for DNA shed by cancer cells into the bloodstream. Cancer DNA carries chemical tags in patterns that differ from healthy cells. Galleri reads those patterns to look for a signal shared by more than 50 types of cancer.
If it finds a cancer signal, Galleri also predicts where in the body the signal most likely came from. That tells your physician where to look first.
Galleri is not a hereditary genetic test. It does not tell you whether you carry an inherited gene change, such as BRCA. If cancer runs in your family, ask your physician about hereditary genetic testing as a separate conversation.
What the Research Shows
Galleri has been studied in two of the largest cancer screening trials ever run, with more than 175,000 participants combined.
Why Our Members Choose Galleri
- It looks for cancers that have no other screening test, including pancreatic, ovarian, esophageal, and liver cancer.
- It points to where to look. A predicted origin means a targeted workup, not a head-to-toe search.
- False alarms are uncommon. Fewer than 1 in 200 people without cancer receive a false-positive result.
- It's simple. One blood draw. No fasting, no prep, no radiation.
- Your physician stays with you the whole way. Many people buy Galleri online and get their results with no one to call. At UEM, the physician who knows your history orders the test, explains your results in person, and coordinates any follow-up imaging or referrals.
Who Galleri Is For
Galleri is recommended for adults at higher risk of cancer, such as people age 50 and older. Your physician may also discuss it if you have a strong family history of cancer or other risk factors.
Galleri is not recommended if you are pregnant, are 21 or younger, or are currently being treated for cancer.
Galleri adds to your routine screenings. It does not replace them. Keep up with your mammograms, colonoscopy or stool testing, cervical screening, and lung screening as recommended.
How It Works at Upper Echelon Medical
- Talk with your physician. We review your history and risk factors and decide together whether Galleri makes sense for you.
- Have your blood drawn. A quick draw in our Fullerton office. No fasting needed.
- Review your results together. Results typically return in about two weeks. Your physician goes over them with you in a visit, not by form letter.
- If a cancer signal is detected, your physician orders targeted imaging and testing based on the predicted origin, and coordinates any specialist referrals.
- If no cancer signal is detected, you continue your routine screenings, and we discuss whether to repeat Galleri in a year.
Understanding Your Results
No Cancer Signal Detected. This is reassuring, but it does not rule out cancer. Galleri does not find every cancer. In the NHS-Galleri trial, it detected about half of the 12 deadliest cancers and about a third of all cancers diagnosed within a year of testing. Any new symptoms still need prompt attention.
Cancer Signal Detected. This is not a cancer diagnosis. It means further testing is needed to confirm whether cancer is present. In PATHFINDER 2, about 6 in 10 people with this result were diagnosed with cancer after follow-up testing. The rest were not, which is a false positive.
What to Know Before You Test
- False-positive and false-negative results can happen.
- A positive result leads to follow-up imaging or procedures, which have their own costs and, occasionally, risks.
- Galleri is not currently FDA-approved. It is offered as a laboratory-developed test performed in a CLIA-certified, CAP-accredited lab, and requires a physician's order.
- Studies show Galleri finds more cancers, and finds more of them before Stage IV. Whether this helps people live longer is still being studied.
- Insurance and Medicare do not currently cover Galleri.
Pricing for Members
Galleri is available to active Upper Echelon Medical members at our member price of $599 through December 31, 2026, billed separately from your monthly membership. Your membership covers the visits to discuss the test and review your results with your physician.
Frequently Asked Questions
Is Galleri FDA-approved?
Not yet. An FDA advisory committee voted in favor of approval in September 2026, and the FDA's final decision is expected in early 2027. Today, Galleri is offered as a laboratory-developed test that requires a physician's order.
Is Galleri a genetic test?
No. It looks for DNA shed by cancer cells, not inherited gene changes. If cancer runs in your family, ask about hereditary genetic testing separately.
Does Galleri replace my mammogram or colonoscopy?
No. Galleri is designed to be used alongside your recommended screenings, not instead of them.
How often should I take it?
The major studies tested people once a year. Your physician will recommend a schedule based on your risk factors.
Does insurance cover it?
Not at this time. Medicare and most insurance plans do not cover Galleri. Members pay our member price directly.
Can I get Galleri at UEM if I'm not a member?
Galleri is offered to Upper Echelon Medical members so your physician can follow you through results and any next steps. Learn about membership.
Ready to Talk About Galleri?
Ask your UEM physician at your next visit, or message us to set up a time to talk it through.
The Galleri test was developed, and its performance characteristics were determined, by GRAIL, Inc. It has not been cleared or approved by the U.S. Food and Drug Administration. Galleri is performed in a CLIA-certified, CAP-accredited laboratory and requires a prescription. Galleri does not detect all cancers, and a result of No Cancer Signal Detected does not rule out cancer. A Cancer Signal Detected result requires confirmatory diagnostic testing. False-positive and false-negative results occur. Galleri should be used in addition to guideline-recommended cancer screening. This page is for general information and is not medical advice. Galleri is a registered trademark of GRAIL, Inc.
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